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BMCBI
2010
100views more  BMCBI 2010»
14 years 11 months ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
100
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BMCBI
2010
165views more  BMCBI 2010»
14 years 11 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
85
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BMCBI
2008
114views more  BMCBI 2008»
14 years 11 months ago
Visualization of large influenza virus sequence datasets using adaptively aggregated trees with sampling-based subscale represen
Background: With the amount of influenza genome sequence data growing rapidly, researchers need machine assistance in selecting datasets and exploring the data. Enhanced visualiza...
Leonid Zaslavsky, Yiming Bao, Tatiana A. Tatusova
BMCBI
2007
112views more  BMCBI 2007»
14 years 11 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2006
128views more  BMCBI 2006»
14 years 11 months ago
An interactive tool for visualization of relationships between gene expression profiles
Background: Application of phenetic methods to gene expression analysis proved to be a successful approach. Visualizing the results in a 3-dimentional space may further enhance th...
Peter Ruzanov, Steven J. M. Jones