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BMCBI
2010
149views more  BMCBI 2010»
15 years 24 days ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët
96
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BMCBI
2010
113views more  BMCBI 2010»
15 years 24 days ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2010
135views more  BMCBI 2010»
15 years 24 days ago
GIGA: a simple, efficient algorithm for gene tree inference in the genomic age
Background: Phylogenetic relationships between genes are not only of theoretical interest: they enable us to learn about human genes through the experimental work on their relativ...
Paul D. Thomas
101
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BMCBI
2010
127views more  BMCBI 2010»
15 years 24 days ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
131
Voted
BMCBI
2010
202views more  BMCBI 2010»
15 years 24 days ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
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