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116
Voted
BMCBI
2010
15 years 24 days ago
2010
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
116
Voted
BMCBI
2010
15 years 24 days ago
2010
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
89
Voted
BMCBI
2007
15 years 24 days ago
2007
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
BMCBI
2007
15 years 24 days ago
2007
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
103
Voted
BMCBI
2010
15 years 24 days ago
2010
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...