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BMCBI
2010
123views more  BMCBI 2010»
14 years 9 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
BMCBI
2008
228views more  BMCBI 2008»
14 years 9 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2008
164views more  BMCBI 2008»
14 years 9 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...
CORR
2010
Springer
176views Education» more  CORR 2010»
14 years 9 months ago
Limited Feedback Multi-Antenna Quantization Codebook Design-Part I: Single-User Channels
Abstract--In this two-part paper, we study the design and optimization of limited feedback single-user and multiuser systems with a multiple-antenna base station and single-antenna...
Behrouz Khoshnevis, Wei Yu
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