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BMCBI
2010
175views more  BMCBI 2010»
14 years 10 months ago
Global parameter estimation methods for stochastic biochemical systems
Background: The importance of stochasticity in cellular processes having low number of molecules has resulted in the development of stochastic models such as chemical master equat...
Suresh Kumar Poovathingal, Rudiyanto Gunawan
BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
PeakAnalyzer: Genome-wide annotation of chromatin binding and modification loci
Background: Functional genomic studies involving high-throughput sequencing and tiling array applications, such as ChIP-seq and ChIP-chip, generate large numbers of experimentally...
Mali Salmon-Divon, Heidi Dvinge, Kairi Tammoja, Pa...
BMCBI
2008
155views more  BMCBI 2008»
14 years 10 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2008
142views more  BMCBI 2008»
14 years 10 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2007
167views more  BMCBI 2007»
14 years 10 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
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