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128
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BMCBI
2010
161views more  BMCBI 2010»
15 years 22 days ago
GATExplorer: Genomic and Transcriptomic Explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs
Background: Genome-wide expression studies have developed exponentially in recent years as a result of extensive use of microarray technology. However, expression signals are typi...
Alberto Risueño, Celia Fontanillo, Marcel E...
91
Voted
BMCBI
2010
98views more  BMCBI 2010»
15 years 22 days ago
An optimized TOPS+ comparison method for enhanced TOPS models
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
Mallika Veeramalai, David Gilbert, Gabriel Valient...
BMCBI
2010
156views more  BMCBI 2010»
15 years 22 days ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
116
Voted
BMCBI
2010
143views more  BMCBI 2010»
15 years 22 days ago
Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images
Background: Several algorithms have been proposed for detecting fluorescently labeled subcellular objects in microscope images. Many of these algorithms have been designed for spe...
Pekka Ruusuvuori, Tarmo Äijö, Sharif Cho...
108
Voted
BMCBI
2010
118views more  BMCBI 2010»
15 years 22 days ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
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