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BMCBI
2010
124views more  BMCBI 2010»
15 years 3 days ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
BMCBI
2007
124views more  BMCBI 2007»
14 years 12 months ago
BranchClust: a phylogenetic algorithm for selecting gene families
Background: Automated methods for assembling families of orthologous genes include those based on sequence similarity scores and those based on phylogenetic approaches. The first ...
Maria S. Poptsova, J. Peter Gogarten
CISIS
2008
IEEE
15 years 6 months ago
Inferring the Function of Genes from Synthetic Lethal Mutations
—Techniques for detecting synthetic lethal mutations in double gene deletion experiments are emerging as powerful tool for analysing genes in parallel or overlapping pathways wit...
Oliver Ray, Christopher H. Bryant
KDD
2003
ACM
133views Data Mining» more  KDD 2003»
16 years 11 days ago
Interactive Analysis of Gene Interactions Using Graphical gaussian model
DNA microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Xintao Wu, Yong Ye, Kalpathi R. Subramanian
ISMB
2007
15 years 2 months ago
Automatic genome-wide reconstruction of phylogenetic gene trees
Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...