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BICOB
2010
Springer
15 years 8 days ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
BMCBI
2002
128views more  BMCBI 2002»
14 years 12 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
BIODATAMINING
2008
178views more  BIODATAMINING 2008»
15 years 5 days ago
Clustering-based approaches to SAGE data mining
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Haiying Wang, Huiru Zheng, Francisco Azuaje
BMCBI
2008
99views more  BMCBI 2008»
15 years 5 days ago
Ranking analysis of F-statistics for microarray data
Background: Microarray technology provides an efficient means for globally exploring physiological processes governed by the coordinated expression of multiple genes. However, ide...
Yuan-De Tan, Myriam Fornage, Hongyan Xu
BMCBI
2008
138views more  BMCBI 2008»
15 years 5 days ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski