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BMCBI
2007
143views more  BMCBI 2007»
15 years 11 days ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
NN
2007
Springer
267views Neural Networks» more  NN 2007»
14 years 11 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
RECOMB
2010
Springer
15 years 2 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
EMO
2005
Springer
108views Optimization» more  EMO 2005»
15 years 5 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
GG
2004
Springer
15 years 5 months ago
Tutorial on DNA Computing and Graph Transformation
that graph transformations provide the right level of abstraction, and useful technical tools for studying gene assembly. On the other hand, the gene assembly process inspires a ne...
Tero Harju, Ion Petre, Grzegorz Rozenberg