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JCB
2008
111views more  JCB 2008»
14 years 11 months ago
Sorting Genomes with Centromeres by Translocations
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
Michal Ozery-Flato, Ron Shamir
SCFBM
2008
87views more  SCFBM 2008»
14 years 11 months ago
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....
93
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BIB
2010
89views more  BIB 2010»
14 years 11 months ago
Knowledge-based data analysis comes of age
The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
Michael F. Ochs
137
Voted
NAR
2008
101views more  NAR 2008»
14 years 10 months ago
RNALogo: a new approach to display structural RNA alignment
Regulatory RNAs play essential roles in many essential biological processes, ranging from gene regulation to protein synthesis. This work presents a web-based tool, RNALogo, to cr...
Tzu-Hao Chang, Jorng-Tzong Horng, Hsien-Da Huang
INFORMS
2010
107views more  INFORMS 2010»
14 years 10 months ago
A Class Representative Model for Pure Parsimony Haplotyping
Haplotyping estimation from aligned Single Nucleotide Polymorphism (SNP) fragments has attracted more and more attention in the recent years due to its importance in analysis of m...
Daniele Catanzaro, Alessandra Godi, Martine Labb&e...