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BMCBI
2008
128views more  BMCBI 2008»
15 years 1 days ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
BMCBI
2005
89views more  BMCBI 2005»
14 years 12 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...
FMCAD
2007
Springer
15 years 6 months ago
Analyzing Gene Relationships for Down Syndrome with Labeled Transition Graphs
Abstract— The relationship between changes in gene expression and physical characteristics associated with Down syndrome is not well understood. Chromosome 21 genes interact with...
Neha Rungta, Hyrum Carroll, Eric G. Mercer, Randal...
ISAAC
1998
Springer
99views Algorithms» more  ISAAC 1998»
15 years 4 months ago
On the Multiple Gene Duplication Problem
Abstract. A fundamental problem in computational biology is the determination of the correct species tree for a set of taxa given a set of possibly contradictory gene trees. In rec...
Michael R. Fellows, Michael T. Hallett, Ulrike Ste...
BMCBI
2008
167views more  BMCBI 2008»
15 years 1 days ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren