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ISMB
2004
15 years 1 months ago
Exploiting conserved structure for faster annotation of non-coding RNAs without loss of accuracy
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Zasha Weinberg, Walter L. Ruzzo
TREC
2004
15 years 1 months ago
Information Needs and Automatic Queries
Tarragon Consulting Corporation participated in the adhoc retrieval task of the TREC 2004 Genomics Track. We used a standard deployment of the K2 search engine from Verity, Inc. i...
Richard M. Tong
GECCO
2008
Springer
175views Optimization» more  GECCO 2008»
15 years 1 months ago
Using differential evolution for symbolic regression and numerical constant creation
One problem that has plagued Genetic Programming (GP) and its derivatives is numerical constant creation. Given a mathematical formula expressed as a tree structure, the leaf node...
Brian M. Cerny, Peter C. Nelson, Chi Zhou
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
15 years 2 days ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
BMCBI
2010
190views more  BMCBI 2010»
15 years 2 days ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...