Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Tarragon Consulting Corporation participated in the adhoc retrieval task of the TREC 2004 Genomics Track. We used a standard deployment of the K2 search engine from Verity, Inc. i...
One problem that has plagued Genetic Programming (GP) and its derivatives is numerical constant creation. Given a mathematical formula expressed as a tree structure, the leaf node...
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...