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BMCBI
2011
14 years 4 months ago
SNPPicker: High quality tag SNP selection across multiple populations
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
GECCO
2008
Springer
117views Optimization» more  GECCO 2008»
14 years 10 months ago
CrossNet: a framework for crossover with network-based chromosomal representations
We propose a new class of crossover operators for genetic algorithms (CrossNet) which use a network-based (or graphbased) chromosomal representation. We designed CrossNet with the...
Forrest Stonedahl, William Rand, Uri Wilensky
84
Voted
ICALP
2001
Springer
15 years 2 months ago
Permutation Editing and Matching via Embeddings
Abstract. If the genetic maps of two species are modelled as permutations of (homologous) genes, the number of chromosomal rearrangements in the form of deletions, block moves, inv...
Graham Cormode, S. Muthukrishnan, Süleyman Ce...
BMCBI
2002
109views more  BMCBI 2002»
14 years 9 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
101
Voted
CCS
2009
ACM
15 years 4 months ago
Privacy-preserving genomic computation through program specialization
In this paper, we present a new approach to performing important classes of genomic computations (e.g., search for homologous genes) that makes a significant step towards privacy...
Rui Wang, XiaoFeng Wang, Zhou Li, Haixu Tang, Mich...