In this paper, we introduce the concept of metavariability, i.e., variability with respect to basic variability attributes like binding time or constraints. While the main focus o...
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
—Epidemic models based on nonlinear differential equations have been extensively applied in a variety of systems as diverse as infectious outbreaks, marketing, diffusion of belie...
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...