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BMCBI
2006
239views more  BMCBI 2006»
14 years 11 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
108views more  BMCBI 2006»
14 years 11 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2006
107views more  BMCBI 2006»
14 years 11 months ago
CROPPER: a metagene creator resource for cross-platform and cross-species compendium studies
Background: Current genomic research methods provide researchers with enormous amounts of data. Combining data from different high-throughput research technologies commonly availa...
Jussi Paananen, Markus Storvik, Garry Wong
BMCBI
2006
143views more  BMCBI 2006»
14 years 11 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
BMCBI
2007
141views more  BMCBI 2007»
14 years 11 months ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...