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AI
2010
Springer
14 years 10 months ago
Understanding the scalability of Bayesian network inference using clique tree growth curves
Bayesian networks (BNs) are used to represent and ef ciently compute with multi-variate probability distributions in a wide range of disciplines. One of the main approaches to per...
Ole J. Mengshoel
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen
BMCBI
2007
135views more  BMCBI 2007»
14 years 10 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
BMCBI
2007
153views more  BMCBI 2007»
14 years 10 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
82
Voted
BMCBI
2008
107views more  BMCBI 2008»
14 years 10 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...