Abstract One approach to predict the secondary structure of RNA is the comparative approach. This approach is used when alignment of several homologous sequences of a RNA is availa...
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Protein structure prediction aims to determine the three-dimensional structure of proteins form their amino acid sequences. When a protein does not have similarity (homology) to a...
Correction to Chakrabarti S, Lanczycki CJ, Panchenko AR, Przytycka TM, Thiessen PA and Bryant SH: State of the art: refinement of multiple sequence alignments. BMC Bioinformatics ...
Saikat Chakrabarti, Christopher J. Lanczycki, Anna...
We present a new algorithm that reduces the space complexity of heuristic search. It is most effective for problem spaces that grow polynomially with problem size, but contain lar...