349 search results - page 21 / 70 » The effect of sequence quality on sequence alignment |
BMCBI
2007
14 years 12 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
108
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BMCBI
2006
14 years 11 months ago
2006
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
112
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BMCBI
2011
14 years 3 months ago
2011
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
123
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BMCBI
2011
14 years 6 months ago
2011
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
287
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RECOMB
2012
Springer
13 years 2 months ago
2012
Springer
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...