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» The effect of sequence quality on sequence alignment
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131
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BMCBI
2005
121views more  BMCBI 2005»
15 years 3 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
137
Voted
BMCBI
2010
129views more  BMCBI 2010»
15 years 3 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
137
Voted
BMCBI
2007
140views more  BMCBI 2007»
15 years 3 months ago
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure in
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...
170
Voted
ECAI
2004
Springer
15 years 8 months ago
Learning Complex and Sparse Events in Long Sequences
The Hierarchical Hidden Markov Model (HHMM) is a well formalized tool suitable to model complex patterns in long temporal or spatial sequences. Even if effective algorithms are ava...
Marco Botta, Ugo Galassi, Attilio Giordana
IPPS
2005
IEEE
15 years 9 months ago
High-Performance Direct Pairwise Comparison of Large Genomic Sequences
Many applications in Comparative Genomics lend themselves to implementations that take advantage of common high-performance features in modern microprocessors. However, the common...
Christopher Mueller, Mehmet M. Dalkilic, Andrew Lu...