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» The effect of sequence quality on sequence alignment
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BIBM
2009
IEEE
118views Bioinformatics» more  BIBM 2009»
15 years 7 months ago
Inexact Local Alignment Search over Suffix Arrays
We describe an algorithm for finding approximate seeds for DNA homology searches. In contrast to previous algorithms that use exact or spaced seeds, our approximate seeds may conta...
Mohammadreza Ghodsi, Mihai Pop
BMCBI
2004
211views more  BMCBI 2004»
15 years 3 months ago
GenomeViz: visualizing microbial genomes
Background: An increasing number of microbial genomes are being sequenced and deposited in public databases. In addition, several closely related strains are also being sequenced ...
Rohit Ghai, Torsten Hain, Trinad Chakraborty
160
Voted
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
15 years 9 months ago
Finding Correlations in Functionally Equivalent Proteins by Integrating Automated and Visual Data Exploration
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
IPPS
2006
IEEE
15 years 9 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
15 years 3 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis