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» The effect of sequence quality on sequence alignment
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ICCBR
2003
Springer
15 years 2 months ago
Case Mining from Large Databases
Abstract. This paper presents an approach of case mining to automatically discover case bases from large datasets in order to improve both the speed and the quality of case based r...
Qiang Yang, Hong Cheng
BMCBI
2006
148views more  BMCBI 2006»
14 years 9 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
GIS
2009
ACM
15 years 10 months ago
Map-Matching for Low-Sampling-Rate GPS Trajectories
Map-matching is the process of aligning a sequence of observed user positions with the road network on a digital map. It is a fundamental pre-processing step for many applications...
Yin Lou, Chengyang Zhang, Yu Zheng, Xing Xie, Wei ...
RECOMB
2004
Springer
15 years 9 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...