349 search results - page 9 / 70 » The effect of sequence quality on sequence alignment |
101
click to vote
BMCBI
2010
14 years 11 months ago
2010
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
109
click to vote
RECOMB
2006
Springer
15 years 12 months ago
2006
Springer
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
96
Voted
BMCBI
2006
14 years 11 months ago
2006
Background: Percentage Identity (PID) is frequently quoted in discussion of sequence alignments since it appears simple and easy to understand. However, although there are several...
JCB
2002
14 years 11 months ago
2002
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
111
click to vote
BMCBI
2004
14 years 11 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...