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» The elastic net algorithm and protein structure prediction
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JCB
2006
215views more  JCB 2006»
14 years 11 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
BMCBI
2010
139views more  BMCBI 2010»
14 years 12 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...
JCB
2000
90views more  JCB 2000»
14 years 11 months ago
Geometric Invariant Core for the CL and CH1 Domains of Immunoglobulin Molecules
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
Ognyan Stoyanov, Alexander Kister, Israel Gelfand,...
BMCBI
2006
98views more  BMCBI 2006»
14 years 12 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg
BMCBI
2005
92views more  BMCBI 2005»
14 years 11 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay