144 search results - page 12 / 29 » The evolutionary computation approach to motif discovery in ... |
88
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BMCBI
2007
14 years 9 months ago
2007
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
BMCBI
2006
14 years 9 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
BIB
2006
14 years 9 months ago
2006
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
109
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BMCBI
2011
14 years 4 months ago
2011
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
RECOMB
2002
Springer
15 years 10 months ago
2002
Springer
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...