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BMCBI
2007
115views more  BMCBI 2007»
14 years 9 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
ICML
2005
IEEE
15 years 10 months ago
Predicting protein folds with structural repeats using a chain graph model
Protein fold recognition is a key step towards inferring the tertiary structures from amino-acid sequences. Complex folds such as those consisting of interacting structural repeat...
Yan Liu, Eric P. Xing, Jaime G. Carbonell
BMCBI
2008
132views more  BMCBI 2008»
14 years 9 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
GCB
2004
Springer
223views Biometrics» more  GCB 2004»
15 years 1 months ago
PoSSuMsearch: Fast and Sensitive Matching of Position Specific Scoring Matrices using Enhanced Suffix Arrays
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...
BMCBI
2010
142views more  BMCBI 2010»
14 years 9 months ago
Classification of protein sequences by means of irredundant patterns
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
Matteo Comin, Davide Verzotto