144 search results - page 6 / 29 » The evolutionary computation approach to motif discovery in ... |
BMCBI
2007
14 years 9 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
125
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JCB
2008
14 years 9 months ago
2008
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
75
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GECCO
2005
Springer
15 years 3 months ago
2005
Springer
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
BMCBI
2006
14 years 9 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
ICASSP
2007
IEEE
15 years 4 months ago
2007
IEEE
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...