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112
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BMCBI
2008
171views more  BMCBI 2008»
15 years 2 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri
138
Voted
CSDA
2008
128views more  CSDA 2008»
15 years 2 months ago
Classification tree analysis using TARGET
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
J. Brian Gray, Guangzhe Fan
GC
2008
Springer
15 years 2 months ago
Laplacian Spectrum of Weakly Quasi-threshold Graphs
In this paper we study the class of weakly quasi-threshold graphs that are obtained from a vertex by recursively applying the operations (i) adding a new isolated vertex, (ii) addi...
R. B. Bapat, A. K. Lal, Sukanta Pati
124
Voted
BMCBI
2006
100views more  BMCBI 2006»
15 years 2 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
128
Voted
BMCBI
2007
217views more  BMCBI 2007»
15 years 2 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin