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» The existence of k-radius sequences
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108
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BMCBI
2010
131views more  BMCBI 2010»
15 years 24 days ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
89
Voted
BMCBI
2007
106views more  BMCBI 2007»
15 years 24 days ago
Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
Masashi Fujita, Hisaaki Mihara, Susumu Goto, Nobuy...
93
Voted
BMCBI
2007
151views more  BMCBI 2007»
15 years 24 days ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
89
Voted
BMCBI
2008
125views more  BMCBI 2008»
15 years 24 days ago
Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
Background: The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better unders...
Lesheng Kong, Shoba Ranganathan
122
Voted
BMCBI
2006
100views more  BMCBI 2006»
15 years 22 days ago
Design of microarray probes for virus identification and detection of emerging viruses at the genus level
Background: Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viru...
Cheng-Chung Chou, Te-Tsui Lee, Chun-Houh Chen, Hsi...