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» The greedy path-merging algorithm for sequence assembly
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RECOMB
2001
Springer
13 years 10 months ago
The greedy path-merging algorithm for sequence assembly
Two different approaches to determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly-funded Human Genome Proje...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
JCB
2000
105views more  JCB 2000»
13 years 6 months ago
A Greedy Algorithm for Aligning DNA Sequences
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic progra...
Zheng Zhang 0004, Scott Schwartz, Lukas Wagner, We...
JACM
2002
94views more  JACM 2002»
13 years 6 months ago
The greedy path-merging algorithm for contig scaffolding
Given a collection of contigs and mate-pairs. The Contig Scaffolding Problem is to order and orientate the given contigs in a manner that is consistent with as many mate-pairs as p...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
CEC
2007
IEEE
13 years 10 months ago
Efficient assembling of genome fragments using genetic algorithm enhanced by heuristic search
Abstract-- Shotgun sequencing is the state-of-the-art to decode genome sequence. However this technique needs a lot of fragments. Combining those fragments correctly requires enorm...
Satoko Kikuchi, Goutam Chakraborty
ISMB
1998
13 years 7 months ago
Automated Clustering and Assembly of Large EST Collections
The avMlability of large EST(Expressed Sequence Tag)databases has led to a revolution in the waynew genes are cloned. Difficulties arise, however,due to high error rates and redun...
David P. Yee, Darrell Conklin