Sciweavers

401 search results - page 28 / 81
» The iProClass integrated database for protein functional ana...
Sort
View
BMCBI
2010
112views more  BMCBI 2010»
14 years 9 months ago
PhenoFam-gene set enrichment analysis through protein structural information
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
IJCAI
2007
14 years 11 months ago
Integration of Hybrid Bio-Ontologies using Bayesian Networks for Knowledge Discovery
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
Kenneth McGarry, Sheila Garfield, Nick Morris, Ste...
BMCBI
2010
136views more  BMCBI 2010»
14 years 9 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
JIB
2007
124views more  JIB 2007»
14 years 9 months ago
Analysis of integrated biomolecular networks using a generic network analysis suite
The informative value of biomolecular networks has shifted from being solely information resources for possible cellular partners (whether these embody proteins, (ribo)nucleic aci...
Matthias Oesterheld, Hans-Werner Mewes, Volker St&...