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NAR
2008
152views more  NAR 2008»
14 years 9 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
BMCBI
2007
265views more  BMCBI 2007»
14 years 9 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
NAR
2007
149views more  NAR 2007»
14 years 9 months ago
UniHI: an entry gate to the human protein interactome
Systematic mapping of protein–protein interactions has become a central task of functional genomics. To map the human interactome, several strategies have recently been pursued....
Gautam Chaurasia, Yasir Iqbal, Christian Häni...
BMCBI
2008
81views more  BMCBI 2008»
14 years 9 months ago
A perspective for biomedical data integration: Design of databases for flow cytometry
Background: The integration of biomedical information is essential for tackling medical problems. We describe a data model in the domain of flow cytometry (FC) allowing for massiv...
John Drakos, Marina Karakantza, Nicholas C. Zoumbo...