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BMCBI
2010
138views more  BMCBI 2010»
14 years 9 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2007
157views more  BMCBI 2007»
14 years 9 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
BMCBI
2010
101views more  BMCBI 2010»
14 years 9 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
IPPS
2008
IEEE
15 years 4 months ago
Supporting high performance bioinformatics flat-file data processing using indices
As an essential part of in vitro analysis, biological database query has become more and more important in the research process. A few challenges that are specific to bioinformat...
Xuan Zhang, Gagan Agrawal
BMCBI
2004
123views more  BMCBI 2004»
14 years 9 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...