Background: In systems biology, and many other areas of research, there is a need for the interoperability of tools and data sources that were not originally designed to be integr...
John Boyle, Christopher C. Cavnor, Sarah A. Killco...
We start by describing all the varieties of loops Q that can be defined by autotopisms x, x Q, where x is a composition of two triples, each of which becomes an autotopism when th...
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
Background: As biology becomes an increasingly computational science, it is critical that we develop software tools that support not only bioinformaticians, but also bench biologi...