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BMCBI
2004
151views more  BMCBI 2004»
14 years 11 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
102
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BMCBI
2008
128views more  BMCBI 2008»
14 years 12 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
ICES
2003
Springer
151views Hardware» more  ICES 2003»
15 years 5 months ago
Using Genetic Programming and High Level Synthesis to Design Optimized Datapath
This paper presents a methodology to design optimized electronic systems from high abstraction level descriptions. The methodology uses Genetic Programming in addition to high-leve...
Sérgio G. Araújo, Antônio C. M...
BMCBI
2010
74views more  BMCBI 2010»
14 years 12 months ago
A weighted q-gram method for glycan structure classification
Background: Glycobiology pertains to the study of carbohydrate sugar chains, or glycans, in a particular cell or organism. Many computational approaches have been proposed for ana...
Limin Li, Wai-Ki Ching, Takako Yamaguchi, Kiyoko F...
DATE
2005
IEEE
113views Hardware» more  DATE 2005»
15 years 5 months ago
Hardware-Software Design of a Smart Sensor for Fully-Electronic DNA Hybridization Detection
This paper describes the design of a smart sensor for label-free detection of DNA hybridization. The sensor is based on a direct electrical transduction principle: it measures imp...
Claudio Stagni, Carlotta Guiducci, Massimo Lanzoni...