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ICAISC
2010
Springer
15 years 6 months ago
Computer Assisted Peptide Design and Optimization with Topology Preserving Neural Networks
Abstract. We propose a non-standard neural network called TPNN which offers the direct mapping from a peptide sequence to a property of interest in order to model the quantitative ...
Jörg D. Wichard, Sebastian Bandholtz, Carsten...
ICCD
2003
IEEE
109views Hardware» more  ICCD 2003»
16 years 27 days ago
Independent Test Sequence Compaction through Integer Programming
We discuss the compaction of independent test sequences for sequential circuits. Our first contribution is the formulation of this problem as an integer program, which we then so...
Petros Drineas, Yiorgos Makris
KELSI
2004
Springer
15 years 9 months ago
A Randomized Algorithm for Distance Matrix Calculations in Multiple Sequence Alignment
Multiple sequence alignment (MSA) is a vital problem in biology. Optimal alignment of multiple sequences becomes impractical even for a modest number of sequences [1] since the gen...
Sanguthevar Rajasekaran, Vishal Thapar, Hardik Dav...
JCB
2000
91views more  JCB 2000»
15 years 3 months ago
Scaling Laws and Similarity Detection in Sequence Alignment with Gaps
We study the problem of similarity detection by sequence alignment with gaps, using a recently established theoretical framework based on the morphology of alignment paths. Alignm...
Dirk Drasdo, Terence Hwa, Michael Lässig
BIOCOMP
2009
15 years 5 months ago
Improving Remote Homology Detection Using Sequence Properties and Position Specific Scoring Matrices
Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
Gina Cooper, Michael L. Raymer