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91
Voted
BMCBI
2010
15 years 18 days ago
2010
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
98
Voted
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
15 years 18 days ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
BMCBI
2008
15 years 18 days ago
2008
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
109
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BMCBI
2010
15 years 18 days ago
2010
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
150
click to vote
BMCBI
2008
15 years 18 days ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...