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» The role data model revisited
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RECOMB
2004
Springer
15 years 11 months ago
Probabilistic discovery of overlapping cellular processes and their regulation
In this paper, we explore modeling overlapping biological processes. We discuss a probabilistic model of overlapping biological processes, gene membership in those processes, and ...
Alexis Battle, Eran Segal, Daphne Koller
BMCBI
2006
116views more  BMCBI 2006»
14 years 11 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2011
14 years 2 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
BMCBI
2011
14 years 6 months ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...
EDM
2008
97views Data Mining» more  EDM 2008»
15 years 22 days ago
Using Item-type Performance Covariance to Improve the Skill Model of an Existing Tutor
Using data from an existing pre-algebra computer-based tutor, we analyzed the covariance of item-types with the goal of describing a more effective way to assign skill labels to it...
Philip I. Pavlik, Hao Cen, Lili Wu, Kenneth R. Koe...