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94
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BMCBI
2010
108views more  BMCBI 2010»
15 years 21 days ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
105
Voted
BMCBI
2008
170views more  BMCBI 2008»
15 years 21 days ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
93
Voted
BMCBI
2008
118views more  BMCBI 2008»
15 years 21 days ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
109
Voted
BMCBI
2006
142views more  BMCBI 2006»
15 years 19 days ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
120
Voted
CORR
2006
Springer
135views Education» more  CORR 2006»
15 years 18 days ago
Classification of Ordinal Data
Many real life problems require the classification of items into naturally ordered classes. These problems are traditionally handled by conventional methods intended for the class...
Jaime S. Cardoso
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