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BMCBI
2010
106views more  BMCBI 2010»
14 years 12 months ago
A novel approach for haplotype-based association analysis using family data
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
Yixuan Chen, Xin Li, Jing Li
BMCBI
2010
121views more  BMCBI 2010»
14 years 12 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
BMCBI
2007
194views more  BMCBI 2007»
14 years 12 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
90
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BMCBI
2007
172views more  BMCBI 2007»
14 years 12 months ago
msBayes: Pipeline for testing comparative phylogeographic histories using hierarchical approximate Bayesian computation
Background: Although testing for simultaneous divergence (vicariance) across different population-pairs that span the same barrier to gene flow is of central importance to evoluti...
Michael J. Hickerson, Eli Stahl, Naoki Takebayashi
78
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BMCBI
2008
134views more  BMCBI 2008»
14 years 12 months ago
Stability analysis of mixtures of mutagenetic trees
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
Jasmina Bogojeska, Thomas Lengauer, Jörg Rahn...