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» The statistical significance of the MUC-5 results
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TCBB
2008
126views more  TCBB 2008»
14 years 10 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
BMCBI
2010
182views more  BMCBI 2010»
14 years 10 months ago
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...
Jo A. Helmuth, Grégory Paul, Ivo F. Sbalzar...
BMCBI
2006
169views more  BMCBI 2006»
14 years 10 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...
BMCBI
2006
154views more  BMCBI 2006»
14 years 10 months ago
An improved procedure for gene selection from microarray experiments using false discovery rate criterion
Background: A large number of genes usually show differential expressions in a microarray experiment with two types of tissues, and the p-values of a proper statistical test are o...
James J. Yang, Mark C. K. Yang
BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...