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» The statistical significance of the MUC-5 results
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BMCBI
2007
166views more  BMCBI 2007»
14 years 10 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
112views more  BMCBI 2007»
14 years 10 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2008
108views more  BMCBI 2008»
14 years 10 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2007
217views more  BMCBI 2007»
14 years 10 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin
SIGMETRICS
2008
ACM
119views Hardware» more  SIGMETRICS 2008»
14 years 9 months ago
Network externalities and the deployment of security features and protocols in the internet
Getting new security features and protocols to be widely adopted and deployed in the Internet has been a continuing challenge. There are several reasons for this, in particular ec...
Marc Lelarge, Jean Bolot