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BMCBI
2007
115views more  BMCBI 2007»
14 years 10 months ago
How accurate and statistically robust are catalytic site predictions based on closeness centrality?
Background: We examine the accuracy of enzyme catalytic residue predictions from a network representation of protein structure. In this model, amino acid α-carbons specify vertic...
Eric Chea, Dennis R. Livesay
MICCAI
2009
Springer
15 years 10 months ago
Tensor-Based Morphometry with Mappings Parameterized by Stationary Velocity Fields in Alzheimer's Disease Neuroimaging Initiativ
Tensor-based morphometry (TBM) is an analysis technique where anatomical information is characterized by means of the spatial transformations between a customized template and obse...
Ernesto Zacur, Matías Nicolás Bossa,...
BMCBI
2006
148views more  BMCBI 2006»
14 years 10 months ago
Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
Veronica Vinciotti, Xiaohui Liu, Rolf Turk, Emile ...
JCB
2008
106views more  JCB 2008»
14 years 10 months ago
Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment
Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
James O. Wrabl, Nick V. Grishin
BMCBI
2005
110views more  BMCBI 2005»
14 years 9 months ago
Discovery of protein-protein interactions using a combination of linguistic, statistical and graphical information
Background: The rapid publication of important research in the biomedical literature makes it increasingly difficult for researchers to keep current with significant work in their...
James W. Cooper, Aaron Kershenbaum