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» The system-resonance approach in modeling genetic structures
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DASFAA
2005
IEEE
209views Database» more  DASFAA 2005»
15 years 3 months ago
PADS: Protein Structure Alignment Using Directional Shape Signatures
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
SAC
2004
ACM
15 years 3 months ago
Combining analysis and synthesis in a model of a biological cell
for ideas, and then abstract away from these ideas to produce algorithmic processes that can create problem solutions in a bottom-up manner. We have previously described a top-dow...
Ken Webb, Tony White
BMCBI
2006
161views more  BMCBI 2006»
14 years 9 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2010
178views more  BMCBI 2010»
14 years 9 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
CP
2003
Springer
15 years 2 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...