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» The system-resonance approach in modeling genetic structures
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88
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GECCO
2006
Springer
202views Optimization» more  GECCO 2006»
15 years 1 months ago
Inference of genetic networks using S-system: information criteria for model selection
In this paper we present an evolutionary approach for inferring the structure and dynamics in gene circuits from observed expression kinetics. For representing the regulatory inte...
Nasimul Noman, Hitoshi Iba
BIOINFORMATICS
2007
83views more  BIOINFORMATICS 2007»
14 years 9 months ago
Exploring biological network structure using exponential random graph models
Motivation: The functioning of biological networks depends in large part on their complex underlying structure. When studying their systemic nature many modeling approaches focus ...
Zachary M. Saul, Vladimir Filkov
CSB
2002
IEEE
169views Bioinformatics» more  CSB 2002»
15 years 2 months ago
Bayesian Network and Nonparametric Heteroscedastic Regression for Nonlinear Modeling of Genetic Network
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
Seiya Imoto, SunYong Kim, Takao Goto, Sachiyo Abur...
101
Voted
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
14 years 10 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
87
Voted
BMCBI
2010
138views more  BMCBI 2010»
14 years 9 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi