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BMCBI
2007
113views more  BMCBI 2007»
14 years 12 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
PR
2008
218views more  PR 2008»
14 years 11 months ago
Automatic feature localisation with constrained local models
We present an efficient and robust method of locating a set of feature points in an object of interest. From a training set we construct a joint model of the appearance of each fe...
David Cristinacce, Timothy F. Cootes
INTERNET
2007
182views more  INTERNET 2007»
14 years 11 months ago
Analysis of Caching and Replication Strategies for Web Applications
Replication and caching mechanisms are often employed to enhance the performance of Web applications. In this article, we present a qualitative and quantitative analysis of state-...
Swaminathan Sivasubramanian, Guillaume Pierre, Maa...
BMCBI
2004
174views more  BMCBI 2004»
14 years 11 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
EVOW
2010
Springer
14 years 10 months ago
Finding Gapped Motifs by a Novel Evolutionary Algorithm
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Chengwei Lei, Jianhua Ruan