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BMCBI
2004
97views more  BMCBI 2004»
14 years 9 months ago
Performance of a genetic algorithm for mass spectrometry proteomics
Background: Recently, mass spectrometry data have been mined using a genetic algorithm to produce discriminatory models that distinguish healthy individuals from those with cancer...
Neal O. Jeffries
BMCBI
2004
161views more  BMCBI 2004»
14 years 9 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi
BMCBI
2004
165views more  BMCBI 2004»
14 years 9 months ago
Analysis of oligonucleotide array experiments with repeated measures using mixed models
Background: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients...
Hao Li, Constance L. Wood, Thomas V. Getchell, Mar...
BMCBI
2004
106views more  BMCBI 2004»
14 years 9 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
BMCBI
2004
91views more  BMCBI 2004»
14 years 9 months ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl
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