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BMCBI
2010
119views more  BMCBI 2010»
14 years 7 months ago
The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumour
Background: Proton Magnetic Resonance (MR) Spectroscopy (MRS) is a widely available technique for those clinical centres equipped with MR scanners. Unlike the rest of MR-based tec...
Alexander Pérez-Ruiz, Margarida Julià...
BMCBI
2010
108views more  BMCBI 2010»
14 years 7 months ago
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Background: The opportunities for bacterial population genomics that are being realised by the application of parallel nucleotide sequencing require novel bioinformatics platforms...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2010
121views more  BMCBI 2010»
14 years 7 months ago
A grammar-based distance metric enables fast and accurate clustering of large sets of 16S sequences
Background: We propose a sequence clustering algorithm and compare the partition quality and execution time of the proposed algorithm with those of a popular existing algorithm. T...
David J. Russell, Samuel F. Way, Andrew K. Benson,...
BMCBI
2010
108views more  BMCBI 2010»
14 years 7 months ago
Prediction of RNA secondary structure by maximizing pseudo-expected accuracy
Background: Recent studies have revealed the importance of considering the entire distribution of possible secondary structures in RNA secondary structure predictions; therefore, ...
Michiaki Hamada, Kengo Sato, Kiyoshi Asai
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BMCBI
2010
161views more  BMCBI 2010»
14 years 7 months ago
LTC: a novel algorithm to improve the efficiency of contig assembly for physical mapping in complex genomes
Background: Physical maps are the substrate of genome sequencing and map-based cloning and their construction relies on the accurate assembly of BAC clones into large contigs that...
Zeev Frenkel, Etienne Paux, David I. Mester, Cathe...
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