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BMCBI
2010
83views more  BMCBI 2010»
14 years 9 months ago
An effective approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking
Background: Determination of protein-DNA complex structures with both NMR and X-ray crystallography remains challenging in many cases. High Ambiguity-Driven DOCKing (HADDOCK) is a...
Chun-Chi Chou, M. Rajasekaran, Chinpan Chen
BMCBI
2010
99views more  BMCBI 2010»
14 years 9 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BMCBI
2008
146views more  BMCBI 2008»
14 years 9 months ago
EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries
Background: Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as U...
Robin P. Smith, William J. Buchser, Marcus B. Lemm...
BMCBI
2010
123views more  BMCBI 2010»
14 years 9 months ago
eGIFT: Mining Gene Information from the Literature
Background: With the biomedical literature continually expanding, searching PubMed for information about specific genes becomes increasingly difficult. Not only can thousands of r...
Catalina O. Tudor, Carl J. Schmidt, K. Vijay-Shank...
BMCBI
2010
240views more  BMCBI 2010»
14 years 9 months ago
TAM: A method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
Background: MicroRNAs (miRNAs) are a class of important gene regulators. The number of identified miRNAs has been increasing dramatically in recent years. An emerging major challe...
Ming Lu, Bing Shi, Juan Wang, Qun Cao, Qinghua Cui
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