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152
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BMCBI
2010
15 years 3 months ago
2010
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
138
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BMCBI
2008
15 years 3 months ago
2008
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
135
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BMCBI
2008
15 years 3 months ago
2008
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
148
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BMCBI
2008
15 years 3 months ago
2008
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
126
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BMCBI
2008
15 years 3 months ago
2008
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...