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BMCBI
2007
129views more  BMCBI 2007»
14 years 10 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2007
179views more  BMCBI 2007»
14 years 10 months ago
Automated smoother for the numerical decoupling of dynamics models
Background: Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a pa...
Marco Vilela, Carlos Cristiano H. Borges, Susana V...
BMCBI
2010
151views more  BMCBI 2010»
14 years 10 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
BMCBI
2010
127views more  BMCBI 2010»
14 years 10 months ago
Deriving enzymatic and taxonomic signatures of metagenomes from short read data
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
Uri Weingart, Erez Persi, Uri Gophna, David Horn
BMCBI
2008
242views more  BMCBI 2008»
14 years 10 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...